Sequencing offers clues to progression toward multiple myeloma

(Dana-Farber Cancer Institute) Researchers at Dana-Farber Cancer Institute have carried out the largest genomic analysis of patients with smoldering multiple myeloma (SMM), a precursor to full-blown blood cancer that doesn't show outward symptoms. The next-generation sequencing project 'will help to explain the biology of the disease and how it unfolds through time from asymptomatic stages to symptomatic ones,' said Mark Bustoros, M.D., a postdoctoral fellow in the lab of Irene Ghobrial, M.D.